| Eredivisie | |||
| 7-8-2022 | N.E.C. - FC Twente | 0-1 | [details] |
| 14-8-2022 | FC Twente - Fortuna Sittard | 3-0 | [details] |
| 28-8-2022 | FC Volendam - FC Twente | 1-0 | [details] |
| 31-8-2022 | FC Twente - Excelsior Rotterdam | 4-0 | [details] |
| 3-9-2022 | FC Twente - PSV | 2-1 | [details] |
| 11-9-2022 | AZ - FC Twente | 1-1 | [details] |
| 18-9-2022 | SC Heerenveen - FC Twente | 2-1 | [details] |
| 1-10-2022 | FC Twente - Vitesse | 3-0 | [details] |
| 9-10-2022 | Feyenoord - FC Twente | 2-0 | [details] |
| 16-10-2022 | FC Twente - FC Groningen | 3-0 | [details] |
| 23-10-2022 | SC Cambuur - FC Twente | 0-1 | [details] |
| 30-10-2022 | FC Twente - RKC Waalwijk | 3-0 | [details] |
| 6-11-2022 | FC Twente - Go Ahead Eagles | 1-1 | [details] |
| 11-11-2022 | Sparta - FC Twente | 1-1 | [details] |
| 6-1-2023 | FC Twente - FC Emmen | 2-0 | [details] |
| 14-1-2023 | Ajax - FC Twente | 0-0 | [details] |
| 22-1-2023 | FC Twente - FC Utrecht | 2-0 | [details] |
| 25-1-2023 | Vitesse - FC Twente | 2-2 | [details] |
| 29-1-2023 | FC Twente - Feyenoord | 1-1 | [details] |
| 5-2-2023 | FC Groningen - FC Twente | 1-1 | [details] |
| 12-2-2023 | FC Twente - FC Volendam | 3-0 | [details] |
| 19-2-2023 | Go Ahead Eagles - FC Twente | 2-0 | [details] |
| 26-2-2023 | PSV - FC Twente | 3-1 | [details] |
| 4-3-2023 | FC Twente - SC Heerenveen | 3-3 | [details] |
| 11-3-2023 | Fortuna Sittard - FC Twente | 0-3 | [details] |
| 19-3-2023 | FC Twente - AZ | 2-1 | [details] |
| 1-4-2023 | Excelsior Rotterdam - FC Twente | 0-0 | [details] |
| 9-4-2023 | FC Twente - SC Cambuur | 4-0 | [details] |
| 16-4-2023 | FC Utrecht - FC Twente | 1-0 | [details] |
| 23-4-2023 | FC Twente - Sparta | 3-3 | [details] |
| 7-5-2023 | FC Emmen - FC Twente | 0-3 | [details] |
| 12-5-2023 | FC Twente - N.E.C. | 4-0 | [details] |
| 21-5-2023 | RKC Waalwijk - FC Twente | 0-5 | [details] |
| 28-5-2023 | FC Twente - Ajax | 3-1 | [details] |
| KNVB Beker | |||
| 10-1-2023 | FC Twente - Telstar | 3-1 | [details] |
| 9-2-2023 | FC Twente - Ajax | 0-1 | [details] |
| Europa Cup | |||
| 4-8-2022 | FC Čukarički Belgrado - FC Twente | 1-3 | [details] |
| 11-8-2022 | FC Twente - FC Čukarički Belgrado | 4-1 | [details] |
| 18-8-2022 | ACF Fiorentina - FC Twente | 2-1 | [details] |
| 25-8-2022 | FC Twente - ACF Fiorentina | 0-0 | [details] |
| Play-offs | |||
| 1-5-2023 | SC Heerenveen - FC Twente | 1-2 | [details] |
| 4-6-2023 | FC Twente - SC Heerenveen | 4-0 | [details] |
| 8-6-2023 | Sparta - FC Twente | 1-1 | [details] |
| 11-6-2023 | FC Twente - Sparta | 1-0 | [details] |
| Vriendschappelijk | |||
| 25-6-2022 | Bonifatius Boys - FC Twente | 0-11 | [details] |
| 3-7-2022 | FC Twente - FC Nordsjaelland | 1-0 | [details] |
| 8-7-2022 | Fortuna Düsseldorf - FC Twente | 1-5 | [details] |
| 16-7-2022 | FC Twente - Werder Bremen | 3-3 | [details] |
| 22-7-2022 | FC Twente - Antalyaspor | 1-3 | [details] |
| 22-7-2022 | FC Twente - FC Schalke 04 | 3-1 | [details] |
| 29-7-2022 | FC Twente - Bologna | 4-1 | [details] |
| 14-9-2022 | FC Groningen - FC Twente | 0-2 | [details] |
| 22-9-2022 | FC Twente - FC Emmen | 0-1 | [details] |
| 10-10-2022 | FC Twente - Go Ahead Eagles | 4-0 | [details] |
| 3-12-2022 | Almere City FC - FC Twente | 1-1 | [details] |
| 10-12-2022 | FC Twente - Sparta | 2-1 | [details] |
| 17-12-2022 | LD Alajuelense - FC Twente | 2-2 | [details] |
| 21-12-2022 | LD Alajuelense - FC Twente | 3-2 | [details] |
| 30-12-2022 | FC Twente - SC Heerenveen | 2-0 | [details] |
| 27-2-2023 | Heracles Almelo - FC Twente | 1-2 | [details] |
| 22-3-2023 | FC Twente - Vfl Bochum | 1-0 | [details] |
| 26-4-2023 | FC Twente - Vitesse | 1-0 | [details] |
| Václav Černý | 11 |
| Gijs Smal | 10 |
| Ricky van Wolfswinkel | 6 |
| Ramiz Zerrouki | 4 |
| Joshua Brenet | 4 |
| Michel Vlap | 3 |
| Virgil Misidjan | 3 |
| Michal Sadílek | 2 |
| Robin Pröpper | 2 |
| Denilho Cleonisse | 1 |
| Sem Steijn | 1 |
| Manfred Ugalde | 1 |
| Mathias Kjølø | 1 |
